Effectiveness of INTEGRA (Glucose Telemonitoring) on Quality of Life and Medication Adherence in Type 2 Diabetes at Puskesmas Cilacap Tengah I

Lina Nur’aini; Dwi Indah  Iswanti; Sonhaji Sonhaji

doi:10.70716/mohr.v4i3.675

Authors

Lina Nur’aini Magister Keperawatan, Ilmu Keperawatan dan Kesehatan, Univesitas Karya Husada Semarang, Indonesia
Dwi Indah Iswanti Magister Keperawatan, Ilmu Keperawatan dan Kesehatan, Univesitas Karya Husada Semarang, Indonesia
Sonhaji Magister Keperawatan, Ilmu Keperawatan dan Kesehatan, Univesitas Karya Husada Semarang, Indonesia

DOI:

https://doi.org/10.70716/mohr.v4i3.675

Keywords:

blood glucose telemonitoring, health-related quality of life, integra, medication adherence, type 2 diabetes mellitus

Abstract

Type 2 Diabetes Mellitus requires continuous management. Health-Related Quality of Life (HRQoL) and medication adherence are important indicators of therapy success that are often affected by a decline in ongoing understanding. Analyze the effect of INTEGRA (Blood Glucose Telemonitoring Intervention) on HRQoL and medication adherence of Type 2 Diabetes Mellitus patients at the Cilacap Tengah I Community Health Center. This quasi-experimental pretest-posttest study with a control group involved 138 respondents (69 intervention, 69 control) selected by purposive sampling and simple randomization. The intervention group received the INTEGRA program for 12 weeks; the control group received standard care. HRQoL was measured using the WHOQOL-BREF and complemented by the Summary of Diabetes Self-Care Activity (SDSCA). Analysis used Mann-Whitney, Wilcoxon, and ANOVA. The intervention group showed an increase in SDSCA scores; the control did not change significantly. The WHOQOL-BREF intervention score increased, whereas the control remained stable. ANOVA showed INTEGRA increased confounding variables. INTEGRA effectively improves HRQoL and treatment adherence in patients with Type 2 Diabetes Mellitus. The program is recommended for services in primary health facilities.

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References

Agustina, E., Ali Harokan, & Erma Gustina. (2023). Analisis Kepatuhan Minum Obat Pasien Diabetes Melitus Type 2. Cendekia Medika: Jurnal Stikes Al-Ma'arif Baturaja, 8(2), 326–341. https://doi.org/10.52235/cendekiamedika.v8i2.245

Choudhary, P., Bellido, V., Graner, M., Altpeter, B., Cicchetti, A., Durand-Zaleski, I., & Kristensen, F. B. (2021). The Challenge of Sustainable Access to Telemonitoring Tools for People with Diabetes in Europe: Lessons from COVID-19 and Beyond. Diabetes Therapy, 12(9), 2311–2327. https://doi.org/10.1007/s13300-021-01132-9

Della, A., Subiyanto, P., & Maria, A. (2023). Faktor-Faktor Yang Berhubungan Dengan Kepatuhan Pengobatan Pasien Diabetes Melitus Tipe 2. Jurnal Keperawatan Klinis Dan Komunitas (Clinical and Community Nursing Journal), 7(2), 124. https://doi.org/10.22146/jkkk.83090

Ehtewish, H., Arredouani, A., & El-Agnaf, O. (2022). Diagnostic, Prognostic, and Mechanistic Biomarkers of Diabetes Mellitus-Associated Cognitive Decline. International Journal of Molecular Sciences, 23(11), 1–32. https://doi.org/10.3390/ijms23116144

Eliza, D., Syafhan, N. F., Andrajati, R., & Fitriani, S. W. (2023). Medication Adherence, Glycemic Control and Quality of Life in Patients with Type 2 Diabetes Mellitus: a cross-sectional study. J Sains Farm Klin, 10(1), 21–27. https://doi.org/10.25077/jsfk.10.1.21-27.2023

Erwan, F., Andoko, A., Triyoso, T., & Kurniasih, D. (2025). Medication adherence and management of blood glucose in type 2 diabetes mellitus. Journal Of Mental Health Concerns, 4(4), 1–20. https://doi.org/10.56922/mhc.v4i4.1367

Fandinata, S. S., Putra, D. A., Lubada, E. I., Sari, S. N. P., Devientasari, C., Ernawati, I., Suryandari, M., & Berliana, D. (2026). Association of medication adherence with clinical outcomes and quality of life in type 2 diabetes mellitus patients: a cross-sectional study. Media Penelitian Dan Pengembangan Kesehatan, 36(1), 346–358. https://doi.org/10.34011/jmp2k.v36i1.2218

Fithria, F., Husna, C., Ahyana, A., Nurhidayah, I., & Jannah, S. R. (2022). Self-management Effectiveness on the Quality of Life of Type 2 Diabetes Mellitus Patients during the COVID-19 Pandemic in Aceh, Indonesia. Open Access Maced J Med Sci, 24(10), 492–498. https://doi.org/10.3889/oamjms.2022.9634

Koo, D.-J., Sun-Joon, M., Moon, S., Eun, S., Rhee2, E.-J., Lee, W.-Y., & Park, C.-Y. (2024). Long-Term Glycemic Control Improvement After the Home and Self-Care Program for Patients With Type 1 Diabetes: Real-World–Based Cohort Study. J Med Internet Res, 26(1), 1–30. https://doi.org/10.2196/60023

Kotowicz, M., Koczkodaj, M., Szajewski, P., Zielińska, M., Bieniak, M., Zagórska, A., & Ciećwierz, J. (2026). Continuous glucose monitoring in diabetes management evidence, applications, and future perspectives: A comprehensive review of recent developments. Ann. Acad. Med. Siles, 80(10), 227–232. https://doi.org/10.18794/aams/214253

Mano, D., Ezra, P. J., Marcella, A., & Firmansyah, Y. (2023). Kegiatan pengabdian masyarakat dalam rangka edukasi masyarakat terhadap hipertensi serta deteksi dini penyakit gagal ginjal sebagai komplikasi dari hipertensi. Jurnal Pengabdian Masyarakat Indonesia, 2(2), 34-45. https://doi.org/10.55606/jpmi.v2i2.1776

Pieters, M. M., Fahsen, N., Lozier, M. J., Hug, C., Ishida, K., & Cordon-Rosales, C. (2025). A Quasi-Experimental Pre-Post Assessment of Hand Hygiene Practices and Hand Dirtiness Following a School-Based Educational Campaign. International Journal of Environmental Research and Public Health, 22(8), 1–12. https://doi.org/10.3390/ijerph22081198

Polwiang, S. (2020). The time series seasonal patterns of dengue fever and associated weather variables in Bangkok ( 2003-2017 ). Jurnal Ilmu Budaya, 20(1), 1–10. https://doi.org/10.1186/s12879-020-4902-6

Putri, S. I., Supriyono, N. D., Fajriah, A. S., & Akbar, P. S. (2025). The Effectiveness of Telemedicine for Glycemic (Hba1c) Management of Patients with Diabetes Mellitus Type 2: A Meta-Analysis. Majalah Kesehatan Indonesia, 6(3), 93–106. https://doi.org/10.47679/makein.2025261

Rismawan, M., Handayani, N. M. T., & Rahayuni, I. G. A. R. (2023). Hubungan Kepatuhan Minum Obat Terhadap Kadar Gula Darah Sewaktu Pada Penderita Diabetes Mellitus Tipe 2. Jurnal Riset Media Keperawatan, 6(1), 23–30. https://doi.org/10.51851/jrmk.v6i1.373

Saetang, T., Greeviroj, P., Thavaraputta, S., Santisitthanon, P., Houngngam, N., & Laichuthai, N. (2024). The effectiveness of telemonitoring and integrated personalized diabetes management in people with insulin-treated type 2 diabetes mellitus. Randomized Controlled Trial, 26(11), 5233–5238. https://doi.org/10.1111/dom.15870

Sharma, S., Singh, H., Ahmad, N., Mishra, P., & Tiwari, A. (2015). The role of melatonin in diabetes: Therapeutic implications. Archives of Endocrinology and Metabolism, 59(5), 391–399. https://doi.org/10.1590/2359-3997000000098

Sinaga, R. M., & Ahmed, I. A. (2025). Factors Affecting Medication Adherence among Patients with Type 2 Diabetes: A Review. International Journal of Biotechnology and Biomedicine, 2(1), 1–10. https://doi.org/10.31674/ijbb.2025.v02i01.001

Sukarno, A., & Munthe, E. D. (2026). The Effectiveness of Dia-Care Telemonitoring on Diabetes Outcome among Type 2 Diabetes Patients. Dunia Keperawatan: Jurnal Keperawatan Dan Kesehatan, 9(3), 435–442. https://doi.org/10.1177/002076402

Suprapto, Muhammad, Bte, K. R., & Saputra, M. K. F. (2026). Integrated Education to Improve Treatment Adherence for Type 2 Diabetes Mellitus Patients in Makassar. Jurnal Pengabdian Masyarakat Edukasi, 3(1), 38–46. https://doi.org/10.61099/jpmei.v3i1.172

Suprapto. (2026). Integrated Education to Improve Treatment Adherence for Type 2 Diabetes Mellitus Patients in Makassar. Jurnal Pengabdian Masyarakat Edukasi Indonesia, 3(1), 38–46. https://doi.org/10.61099/jpmei.v3i1.172

Tenekedjiev, K., Panayotova, D., Daboos, M., Ivanova, S., Symes, M., Panayotov, P., & Nikolova, N. (2025). Quasi-Experimental Design for Medical Studies with the Method of the Fuzzy Pseudo-Control Group. Applied Sciences, 15(3), 1–45. https://doi.org/10.3390/app15031370

Vas, P., Rayman, G., Dhatariya, K., & Driver, V. (2020). Effectiveness of interventions to enhance healing of chronic foot ulcers in diabetes: a systematic review. Diabetes/Metabolism Research and Reviews, 36(1). https://doi.org/10.1002/dmrr.3284

Xiao, Y., Wang, Z., Zhang, L., Xie, N., Chen, F., Song, Z., & Zhao, S. (2025). Effectiveness of Digital Diabetes Management Technology on Blood Glucose in Patients With Type 2 Diabetes at Home: Systematic Review and Meta-Analysis. Journal of Medical Internet Research, 27(10), 100–130. https://doi.org/10.2196/66441

Zhang, A., Wang, J., Wan, X., Zhang, Z., Zhao, S., Guo, Z., & Wang, C. (2022). A Meta-Analysis of the Effectiveness of Telemedicine in Glycemic Management among Patients with Type 2 Diabetes in Primary Care. International Journal of Environmental Research and Public Health, 19(7), 4173. https://doi.org/10.3390/ijerph19074173

Zhang, D., & Huang, Q. (2020). Encapsulation of astragaloside with matrix metalloproteinase-2-responsive hyaluronic acid end-conjugated polyamidoamine dendrimers improves wound healing in …. Journal of Biomedical Nanotechnology, 16(8). https://doi.org/10.1166/jbn.2020.2971