Maternal and Environmental Factors Associated with Low Birth Weight: A Systematic Literature Review

Authors

  • Ayu Yuliani Sekriptini Faculty of Medicine, Poltekkes Tasikmalaya, Tasikmalaya, Indonesia
  • Oktia Woro Kasmini Handayani Faculty of Medicine, Universitas Negeri Semarang, Indonesia
  • Haryono Faculty of Education and Psychology, Universitas Negeri Semarang, Indonesia

DOI:

https://doi.org/10.70716/mohr.v4i2.481

Keywords:

low birth weight, maternal factors, environmental factors, systematic literature review, PRISMA

Abstract

This study aims to examine maternal and environmental factors associated with low birth weight through a systematic literature review. The review followed the PRISMA framework to ensure a structured, transparent process for identification, screening, eligibility, and inclusion. Literature searching was conducted using the Directory of Open Access Journals (DOAJ) for studies published between 2022 and 2026. A total of 320 records were identified; after duplicate removal, 308 were screened, and 10 studies were included in the final synthesis. The findings indicate that low birth weight is a multidimensional outcome shaped by the interaction of maternal and environmental determinants. The most consistent maternal factors include preeclampsia, anemia, poor nutritional status, inadequate micronutrient intake, adverse reproductive history, and unhealthy lifestyle behaviors. Environmental determinants such as air pollution, household smoke exposure, solid fuel use, and poor housing conditions were also strongly associated with low birth weight. This review highlights that isolated factors cannot explain low birth weight; rather, it arises from cumulative biological and environmental vulnerabilities. The study contributes to strengthening integrative understanding and supports the development of comprehensive maternal and environmental health interventions.

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References

Andemariam, Z., Teages, E., Zerezghi, H., & Seyoum, Y. (2023). Environmental and maternal anthropometric determinants for low birth weight in maternity hospitals in Asmara, Eritrea. MOJ Public Health, 12. https://doi.org/10.15406/mojph.2023.12.00406

Arabzadeh, H., Doosti-Irani, A., Kamkari, S., Farhadian, M., Elyasi, E., & Mohammadi, Y. (2024). The maternal factors associated with infant low birth weight: An umbrella review. BMC Pregnancy and Childbirth, 24. https://doi.org/10.1186/s12884-024-06487-y

Brackett, A., & Batten, J. (2022). Ensuring rigor in systematic reviews: Part 7, critical appraisal of systematic review quality. Heart & Lung, 53, 32–35. https://doi.org/10.1016/j.hrtlng.2022.01.008

Buciu, V.-B., Ciurescu, S., Șerban, D., Novacescu, D., Nicoleta, N., Tomescu, L., Rusu, E. L., Sas, I., Ionac, M., & Chiriac, V. (2025). The Compounded Risk of Maternal Anemia and Preeclampsia: Neonatal Outcomes and Predictive Modeling in a Low-Resource Tertiary Center. Journal of Clinical Medicine, 14(14), 5051. https://doi.org/10.3390/jcm14145051

Budha, N., Shrestha, T., & Adhikari, S. (2025). Contributing Factors for Low Birth Weight among Newborns in a Maternity Hospital, Kathmandu. Journal of Birgunj Nursing Campus. https://doi.org/10.70397/jbnc.60

Dagher, D., & Khan, M. (2025). Writing a systematic review and meta analysis: A step by step guide. Sports Health, 17(5), 885–890. https://doi.org/10.1177/19417381251364686

Devaguru, A., Gada, S., Potpalle, D., Eshwar, M., & Purwar, D. (2023). The prevalence of low birth weight among newborn babies and its associated maternal risk factors: A hospital based cross sectional study. Cureus, 15. https://doi.org/10.7759/cureus.38587

Diabelková, J., Rimárová, K., Urdzík, P., Dorko, E., Houžvičková, A., Andraščíková, Š., Drabiščák, E., & Škrečková, G. (2022). Risk factors associated with low birth weight. Central European Journal of Public Health, 30(Supplement), S43–S49. https://doi.org/10.21101/cejph.a6883

Dola, S., & Valderrama, C. (2024). Exploring parental factors influencing low birth weight on the 2022 CDC natality dataset. BMC Medical Informatics and Decision Making, 24. https://doi.org/10.1186/s12911-024-02783-x

Gusenbauer, M., & Gauster, S. P. (2025). How to search for literature in systematic reviews and meta-analyses: A comprehensive step-by-step guide. Technological Forecasting and Social Change, 212, 123833. https://doi.org/10.1016/j.techfore.2024.123833

Handayani, F., Indasah, I., & Puspitasari, Y. (2025). Analysis of maternal risk factors for low birth weight infants at the public health center. Indonesian Journal of Global Health Research, 7(2). https://doi.org/10.37287/ijghr.v7i2.5682

Herwanto, E., Hudiyanto, P., & Muhammad, I. (2024). Factors of maternal influence on low birth weight. Asian Journal of Health Research, 3(1). https://doi.org/10.55561/ajhr.v3i1.144

Hossain, M., Begum, S., Neyma, M., Hossain, K., Faruk, M., Hossain, S., & Afnan, H. (2025). Parental socioeconomic, demographic, and neonatal factors influencing infants' low birth weight: A cross-sectional study in Bangladesh. Health Science Reports, 8. https://doi.org/10.1002/hsr2.71146

Ivaturi, S., Elhussein, M., Anireddy, S., & Narayan, J. (2025). Prevalence of low birth weight infants and their association with maternal risk factors: A cross sectional study. International Journal of Scientific Reports. https://doi.org/10.18203/issn.2454-2156.intjscirep20252523

Jeena, P., Asharam, K., Mitku, A., Naidoo, P., & Naidoo, R. (2020). Maternal demographic and antenatal factors, low birth weight and preterm birth: Findings from the Mother and Child in the Environment birth cohort, Durban, South Africa. BMC Pregnancy and Childbirth, 20. https://doi.org/10.1186/s12884-020-03328-6

Kolaski, K., Logan, L. R., & Ioannidis, J. P. A. (2023). Guidance to best tools and practices for systematic reviews. Systematic Reviews, 12, 96. https://doi.org/10.1186/s13643-023-02255-9

Lindsay, C., Blancquaert, I., & Rousseau, F. (2025). Tools used to appraise the quality of studies included in systematic reviews and meta analyses in human genetics: A systematic review. European Journal of Human Genetics, 33, 1392–1401. https://doi.org/10.1038/s41431-025-01861-6

Lu, X., Zhang, Y., Jiang, R., Qin, G., Ge, Q., Zhou, X., Zhou, Z., Ni, Z., & Zhuang, X. (2024). Interpregnancy interval, air pollution, and the risk of low birth weight: A retrospective study in China. BMC Public Health, 24. https://doi.org/10.1186/s12889-024-19711-3

Lutfia, S., & Farizi, S. (2024). Maternal risk factors for low birth weight infants: A systematic review study. World Journal of Advanced Research and Reviews, 21(1). https://doi.org/10.30574/wjarr.2024.21.1.0151

Mizuno, S., Nagaie, S., Tamiya, G., Kuriyama, S., Obara, T., Ishikuro, M., Tanaka, H., Kinoshita, K., Sugawara, J., Yamamoto, M., Yaegashi, N., & Ogishima, S. (2023). Establishment of the early prediction models of low birth weight reveals influential genetic and environmental factors: A prospective cohort study. BMC Pregnancy and Childbirth, 23. https://doi.org/10.1186/s12884-023-05919-5

Nishihama, Y., Nakayama, S., & Tabuchi, T. (2022). Population-attributable fractions of risk factors for low birth weight in the Japan Environment and Children's Study. Environment International, 170, 107560. https://doi.org/10.1016/j.envint.2022.107560

Ruan, X., Chen, K., Li, Z., Wei, J., Chen, Y., Zou, Q., Peng, Y., Luo, M., Sun, M., Wang, T., & Qin, J. (2025). The impact of maternal health and lifestyle on low birth weight: A prospective cohort study. Italian Journal of Pediatrics, 51. https://doi.org/10.1186/s13052-025-02080-x

Rumrich, I., Korhonen, A., Forsberg, B., Frohn, L., Geels, C., Brandt, J., & Hänninen, O. (2025). The association of low-level air pollution with birth weight in a register-based study: Potential effects below WHO AQ guidelines. BMC Pregnancy and Childbirth, 25. https://doi.org/10.1186/s12884-025-07219-6

Sinsamala, R. M., Johannessen, A., Bertelsen, R., Accordini, S., Brandt, J., Frohn, L., Geels, C., Gislason, T., Holm, M., Janson, C., Markevych, I., Orru, H., Real, F. G., Sigsgaard, T., Skulstad, S., Svanes, C., & Marcon, A. (2024). Pregnancy outcomes as related to in utero exposure to air pollution and greenness: The Life-GAP Project. Environmental Epidemiology, 8. https://doi.org/10.1097/EE9.0000000000000318

Tamene, A., Habte, A., Tagesse, M., Sewalem, Z., & Afework, A. (2023). Using household survey data to explore the effects of the domiciliary environment on weight at birth: A multilevel mixed-effects analysis of the 2016 Ethiopian Demographic Health Survey. BMC Pregnancy and Childbirth, 23. https://doi.org/10.1186/s12884-023-05521-9

Vats, H., Saxena, R., Sachdeva, M., Walia, G., & Gupta, V. (2023). Maternal risk factors associated with term low birth weight in India: A review. Anthropological Review, 85(4). https://doi.org/10.18778/1898-6773.85.4.05

Wang, C., Tang, Q., Xiao, W., Shen, W., Zong, Y., You, Z., Tang, X., & Huang, F. (2025). The impact of air pollution exposure on adverse pregnancy outcomes: A time-series study. International Journal of Environmental Health Research. https://doi.org/10.1080/09603123.2025.2483349

Yamamoto, S. S., Premji, S., Saini, V., McDonald, S. W., & Jhangri, G. S. (2023). Investigating associations between maternal stress, smoking, and adverse birth outcomes: Evidence from the All Our Families cohort. BMC Pregnancy and Childbirth, 23. https://doi.org/10.1186/s12884-023-06029y

Zuvarcan, D. A., Putra, D. A., & Martuti, S. (2024). Correlation between Preeclampsia and Infant Low Birth Weight at Dr. Moewardi Hospital, Surakarta, Central Java, Indonesia. Journal of Maternal and Child Health, 9(1). https://doi.org/10.26911/thejmch.2024.09.01.03

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Published

2026-05-12

How to Cite

Sekriptini, A. Y., Handayani, O. W. K., & Haryono, H. (2026). Maternal and Environmental Factors Associated with Low Birth Weight: A Systematic Literature Review. Media of Health Research, 4(2), 116–130. https://doi.org/10.70716/mohr.v4i2.481